High school student examining a slide under a microscope.



Pandem-Sim™ is a comprehensive educational project designed to increase high school students’ knowledge of human infectious disease, microorganisms, the immune system, and epidemiological processes investigating disease outbreaks and health conditions.

What's Pandem-Sim?

Pandem-Sim™ is an intense and immersive learning experience that engages your students in a live simulation to analyze medical reports from around the world. Students quickly diagnose and treat an array of infectious diseases, study the data trends, and issue recommendations for prevention and control through public health alerts. With the help of computers, the Internet, and a video conference or webcam connection, students interact with a "Chief Epidemiologist" at the Challenger Learning Center® in Wheeling, WV. Together, teams of students use their critical thinking skills and scientific knowledge to resolve disease outbreaks and try to prevent epidemics. During their mission, students become part of an emergency epidemiology team assembled to help resolve worldwide outbreaks. Stationed in a simulated Pandem Disease Center (PDC), students receive alerts from health officials in the field and must respond quickly to help prevent further disease cases.

High school student participating in a Pandem-Sim mission.

Live Simulation

Become an emergency medical specialist/epidemiologist in this live simulation conducted through web/videoconferencing. You and your teammates resolve disease outbreaks as you work to help healthcare workers and victims across the globe. The Pandem-Sim live simulation provides an authentic way for high school students to apply science knowledge and skills. The mission curriculum is based on national and state science standards related to pathogens, human health, and the disease process. To conduct the mission, students become part of a Pandem-Sim team. They work in a simulated disease center equipped with high-tech computer resources and medical research capabilities, state-of-the-art, high-end communications systems, and dedicated satellites to relay information. Each team consists of three specialist groups: Infectious Disease Specialists, Epi-Analysts, and Disease Transmission Specialists. Typically, each of these groups includes two students, who share a computer to conduct their analyses. They should be seated near the team’s other two groups in order to collaborate often.

Support Curriculum

Pandem-Sim provides support curriculum before each mission to teach students about the different types of microorganisms and how they cause disease.

Microscopic view of influenza virus

Viruses and Prions

How can such simple structures be so puzzling? Click to find out.

Microscopic view of salmonella bacteria


Bacteria were the first living organisms and continue to exist in close relationship to many other species. Click to read more.

Microscopic view of Protozoan


They are not bacteria and they are not viruses. Exactly what are pathogenic protozoans?

Microscopic view of Fungi


Fungi live in the soil, on plants and trees, and in the air. Why do Fungi play an important role in almost all ecosystems?

Microscopic view of Helminth


Depending on where you live, helminth infections are not common. Find out why.

Microscopic view of Yersinia pestis


Many infections and diseases are caused by microorganisms, but not all microorganisms cause disease. Click to find out why.


Pandem-Sim is Tied to Educational Standards

Pandem-Sim is a comprehensive educational project designed to increase high school students’ knowledge of human infectious disease, microorganisms, the immune system, and epidemiological processes investigating disease outbreaks and health conditions. The project is a perfect fit for biology, anatomy and physiology, health, and related classes as well as in some guidance classes that have a careers component. In addition to infectious disease content, students who use Pandem-Sim materials gain a better understanding of how the immune system works to protect us from pathogens, how disease is transmitted, and what they can do to reduce their risks of certain infections and health conditions. And, of course, everything is tied to national standards.

Sign up for e-Missions

Schedule an e-Mission Today!

Contact our team to find out more information on how to schedule an e-Mission™ today!

Register Now!

Train with one of our experts to prepare for your upcoming e-Mission™. Register for a FREE teacher training today!

More e-Missions!

Interested in more live engaging e-Missions™? We offer a variety of live simulations for grades K-12.

Challenger e-Missions Testimonials

Brian Loughran

Technology Assistant, Nipher Middle School

"I can only say again how worthwhile your program is, how engaging for our students, and how grateful I am to get to interact with such a quality team on your end."

Marilyn M.

Teacher, Edinboro Elementary

"My students gained much from this mission. What a wonderful opportunity this is for students to learn problem-solving and critical thinking skills."

Gary Phillips

Director of Technology, Gallia County Local Schools

"The students left the session begging for more! What a wonderful feeling that was…to know that at least for one day we were able to make learning a positive thing for these students. I can guarantee you that these students will remember this e-Mission for years to come."

Pat Ordile  

Camp Participant Grandparent

"Thank you again for providing such a rewarding educational experience for our next generation of leaders!"

Contact Us to Schedule a Mission!

 Our Team and Partners

Wheeling Jesuit University seal logo
Science Education Partnership Award Supported by the National Institutes of Health, SEPA logo
National Institutes of Health NIH logo
Challenger Learning Center at Wheeling, WV logo